NIBHA MISHRA, Senior Scientist, Investigative Toxicology, Takeda Pharmaceuticals

Nibha Mishra works as Senior Scientists and co-chairs the global Neuro-TOS group at Takeda Pharmaceuticals. Where she supports several drug discovery programs. When she is not doing neuroscience, she is analyzing new modalities adverse events data. Before joining Takeda, she was a Researcher at Mass General Hospital where her work was focused on finding novel cure for ALS disease using CRISPR technology. She received her Postdoctoral training on brain specific microRNAs from Hebrew University of Jerusalem, Israel. She has several publications in the peer reviewed journals. During her trainings she also won several fellowships and awards.

Experience:

Takeda Pharmaceuticals
Senior Scientist, Toxicologist 2021-current
Scientist II, Toxicologist 2020-2021

Contributions: Successfully contributed to the evaluation of safety profile of several projects (from CS stage to clinical stage). Developed several assays for screening neurotoxicity profile of compounds. Developed dashboard for adverse events analysis of cell, gene and oligonucleotide therapies.

Co-chair: Global Neurotoxicity Group

Membership: HESI, MIT consortium

Mass General Hospital 2017- 2019
Postdoctoral Fellow (Advisor: Dr.Lagier-Tourenne)
Research areas: Identifying novel therapeutic targets for ALS disease by employing CRISPR screen technology and ALS patient’s cells.

Hebrew University of Jerusalem 2013-2016
Postdoctoral Fellow (Advisor: Prof. Hermona Soreq)
Research areas:Finding novel brain specific miRNA and validating their mRNA targets using miRNAand mRNA-sequencing methods.

Birla Institute of Technology 2006-2013
Lectureship (2006 -2013) while with doing PhD (2009-2013)
(Advisor: Prof. DinakarSasmal)
Research Areas: Studies on enzyme inhibitors identified through computational and pharmacological approaches against Alzheimer’s disease (AD).

Awards

Winner of the SAC 2019 Poster of Distinction Award at Mass General Hospital, Boston, USA.
Best Poster of Distinction award at Post Doc Day in 2019 at Mass General Hospital, Boston, USA.